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A tractor-trailer was stopped on the side of the road around 5:45 a.m. when a box truck traveling westbound near mile marker 29.3 in Tilden Township, struck the back of the tractor-trailer, Pennsylvania State Police said.
The passenger of the box truck was pronounced dead while its driver was taken to Reading Hospital with moderate injuries, police said.
The westbound lanes of I-78 were closed for several hours before reopening around 11 a.m., according to state police.
Anyone who witnessed the crash is urged to call PSP - Hamburg at 610-562-6885.
This is the third deadly crash this week on I-78 in Berks County.
Five people were killed in two separate chain-reaction crashes on Tuesday night, Daily Voice previously reported.
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